| Identification | Back Directory | [Name]
Pyridine, 4-[2-[1-(4-fluorophenyl)cyclopropyl]-4-thiazolyl]- | [CAS]
862250-23-5 | [Synonyms]
FCPT
Pyridine, 4-[2-[1-(4-fluorophenyl)cyclopropyl]-4-thiazolyl]- | [Molecular Formula]
C17H13FN2S | [MDL Number]
MFCD28160536 | [MOL File]
862250-23-5.mol | [Molecular Weight]
296.36 |
| Hazard Information | Back Directory | [Description]
FCPT is an ATP competitive inhibitor of kinesin-5. | [Uses]
FCPT, an ATP competitive inhibitor, induces a tight-binding of kinesin-5 onto microtubules and induced loss of microtubules selectively at the poles of Xenopus extract spindles without altering microtubule dynamics[1]. | [References]
[1] Aaron C Groen, et al. A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci. 2008 Jul 15;121(Pt 14):2293-300. DOI:10.1242/jcs.024018 |
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