| Identification | Back Directory | [Name]
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid | [CAS]
865231-46-5 | [Synonyms]
AMG 837
CS-1283
AMG-837; AMG837
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid
Benzenepropanoic acid, β-1-propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-, (βS)-
(betaS)-beta-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid
(S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid (AMG-837 free acid) 1259389-38-2 (calium salt hydrate) | [Molecular Formula]
C26H21F3O3 | [MDL Number]
MFCD23703041 | [MOL File]
865231-46-5.mol | [Molecular Weight]
438.44 |
| Chemical Properties | Back Directory | [Melting point ]
139-142 °C | [Boiling point ]
565.8±50.0 °C(Predicted) | [density ]
1.251±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
4.20±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
AMG 837 is a potent GPR40 agonist. GPR40 is a polyunsaturated fatty acid receptor that is involved with many systemic effects, which are beneficial for metabolic and inflammatory diseases. GPR40 has also been implicated as a target for treating obesity. | [storage]
Store at -20°C |
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