ChemicalBook--->CAS DataBase List--->868145-09-9

868145-09-9

868145-09-9 Structure

868145-09-9 Structure
IdentificationBack Directory
[Name]

N-(2,4-dimethylphenyl)sulfonyl-2-naphthalen-2-yloxyacetamide
[CAS]

868145-09-9
[Synonyms]

I942
I-942
I 942
N-(2,4-dimethylphenyl)sulfonyl-2-naphthalen-2-yloxyacetamide
[Molecular Formula]

C20H19NO4S
[MOL File]

868145-09-9.mol
[Molecular Weight]

369.43
Chemical PropertiesBack Directory
[density ]

1.279±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

4.99±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

I942 EPAC1 agonist, also known as I942, is a first in class, isoform selective non-cyclic nucleotide (NCN) EPAC1 agonist.
[Uses]

I942 is a first in class, selective non-cyclic nucleotide (NCN) EPAC1 agonist. I942 can attenuate proinflammatory cytokine signalling normally associated with cardiovascular diseases[1].
[References]

[1] Graeme Barker, et al. The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation. J Cardiovasc Dev Dis. 2017 Dec 5;4(4):22. DOI:10.3390/jcdd4040022
Spectrum DetailBack Directory
[Spectrum Detail]

N-(2,4-dimethylphenyl)sulfonyl-2-naphthalen-2-yloxyacetamide(868145-09-9)1HNMR
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