| Identification | Back Directory | [Name]
N-[2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)phenoxy]ethyl]-N-methylglycinehydrochloride | [CAS]
868265-28-5 | [Synonyms]
LY2365109
LY 2365109;LY-2365109
LY 2365109 hydrochloride
N-[2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)phenoxy]ethyl]-N-methylglycinehydrochloride | [Molecular Formula]
C22H27NO5 | [MOL File]
868265-28-5.mol | [Molecular Weight]
385.45 |
| Chemical Properties | Back Directory | [Boiling point ]
556.2±50.0 °C(Predicted) | [density ]
1.187±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
Soluble to 100 mM in DMSO and to 50 mM in ethanol | [form ]
Powder | [pka]
2.27±0.10(Predicted) | [InChI]
InChI=1S/C22H27NO5/c1-22(2,3)17-11-15(16-6-8-19-20(12-16)28-14-27-19)5-7-18(17)26-10-9-23(4)13-21(24)25/h5-8,11-12H,9-10,13-14H2,1-4H3,(H,24,25) | [InChIKey]
FKPLJWGRBCQLTL-UHFFFAOYSA-N | [SMILES]
C(O)(=O)CN(CCOC1=CC=C(C2=CC=C3OCOC3=C2)C=C1C(C)(C)C)C |
| Hazard Information | Back Directory | [Uses]
LY 2365109 Hydrochloride is a potent and selective glycine transporter 1 (GlyT1) inhibitor. | [in vivo]
LY2365109 (0.3-30 mg/kg; p.o.) produces dose-dependent elevations of Sprague–Dawley rats in CSF levels of glycine[1].
| [storage]
Desiccate at RT |
|
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BOC Sciences
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| Tel: |
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https://www.bocsci.com |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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