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Adenine-13C is the 13C labeled Adenine[1]. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[2][3][4]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27. DOI:10.1016/0003-9861(61)90033-9
[3] Griffiths AJF, et al. An Introduction to Genetic Analysis. 7th edition. New York: W. H. Freeman 2000. Structure of DNA.
[4] Reader V. The assay of vitamin B(4). Biochem J. 193024(6):1827-31. DOI:10.1042/bj0241827 |
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