| Identification | More | [Name]
Gramine | [CAS]
87-52-5 | [Synonyms]
(1H-INDOL-3-YLMETHYL)-DIMETHYL-AMINE
3-(DIMETHYLAMINOMETHYL)INDOLE
3-((N,N-DIMETHYLAMINO)METHYL)INDOLE
BETA-DIMETHYLAMINOMETHYLINDOLE
DONAXINE
GRAMINE
n,n-dimethyl-1h-indole-3-methanamine
TIMTEC-BB SBB003799
1H-Indol-3-yl-N,N-dimethylmethanamine
3-((dimethylamino)methyl)-indol
3-Dimethylaminomethylindol (gramin)
b-(Dimethylaminomethyl)indole
Donaxin
Gramin
Indole, 3-[(dimethylamino)methyl]-
n,n-dimethyl-1h-indole-3-methanamin
N,N-Dimethyl-1H-indole-3-methylamine
1H-Indole-3-methanamine, N,N-dimethyl-
indol-3-ylmethyldimethylamine
GCLH/for Cefixime | [EINECS(EC#)]
201-749-8 | [Molecular Formula]
C11H14N2 | [MDL Number]
MFCD00005629 | [Molecular Weight]
174.24 | [MOL File]
87-52-5.mol |
| Chemical Properties | Back Directory | [Appearance]
beige powder | [Melting point ]
132-134 °C (lit.) | [Boiling point ]
295.23°C (rough estimate) | [density ]
1.0715 (rough estimate) | [refractive index ]
1.5500 (estimate) | [Fp ]
167 °C
| [storage temp. ]
Refrigerator (+4°C) | [solubility ]
almost transparency in Methanol | [form ]
Powder | [pka]
17.00±0.30(Predicted) | [color ]
Beige | [Water Solubility ]
PRACTICALLY INSOLUBLE | [Merck ]
4533 | [BRN ]
140521 | [InChI]
1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3 | [InChIKey]
OCDGBSUVYYVKQZ-UHFFFAOYSA-N | [SMILES]
CN(C)Cc1c[nH]c2ccccc12 | [LogP]
2.177 (est) | [CAS DataBase Reference]
87-52-5(CAS DataBase Reference) | [NIST Chemistry Reference]
1H-Indole-3-methanamine, N,N-dimethyl-(87-52-5) | [EPA Substance Registry System]
87-52-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
NL7525000
| [TSCA ]
TSCA listed | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
beige powder | [Uses]
Reactant for preparation of:
- Dopamine D2 receptor antagonists
- Anti-malarial drugs
- 5-indolyl-Mannich bases
- Proliferation inhibitors
- Inhibitors of human mast cell chymase
- Preparation of DL-tryptophan
- Potential detoxification inhibitors of the crucifer phytoalexin brassinin
- 3-vinylindoles
- Serotonin 5-HT6 receptor ligand templates
- Selective protein kinase c delta (PKCδ) down regulators
| [Definition]
ChEBI: Gramine is an aminoalkylindole that is indole carrying a dimethylaminomethyl substituent at postion 3. It has a role as a plant metabolite, a serotonergic antagonist, an antiviral agent and an antibacterial agent. It is an aminoalkylindole, an indole alkaloid and a tertiary amino compound. It is a conjugate base of a gramine(1+). | [General Description]
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | [storage]
Room temperature | [Purification Methods]
Crystallise gramine from diethyl ether, ethanol or acetone. It sublimes at 59o/0.001mm. The hydrochloride crystallises from EtOH/Et2O with m 190.5-191.0o(dec). [Culvenor et al. Aust J Chem 17 1301 1964, Beilstein 22 III/IV 4302, 22/10 V 25.] |
|
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
China Langchem Inc.
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| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
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| Telephone: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
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