| Identification | Back Directory | [Name]
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine | [CAS]
873436-91-0 | [Synonyms]
CS-105
PU-H 71
NSC 750424
PU-H71, >=98%
PU-H71 Trifluoroacetic Acid
8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine
9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine
8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylaMino)propyl)-9H-purin-6-aMine
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
9H-Purine-9-propanamine, 6-amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine USP/EP/BP
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine PU-H71 Trifluoroacetic Acid | [Molecular Formula]
C18H21IN6O2S | [MDL Number]
MFCD28952784 | [MOL File]
873436-91-0.mol | [Molecular Weight]
512.37 |
| Chemical Properties | Back Directory | [Melting point ]
>194oC (dec.) | [Boiling point ]
650.6±65.0 °C(Predicted) | [density ]
1.84 | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
10.16±0.29(Predicted) | [color ]
Off-White to Pale Beige | [InChI]
InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23) | [InChIKey]
SUPVGFZUWFMATN-UHFFFAOYSA-N | [SMILES]
N1C2C(=NC=NC=2N)N(CCCNC(C)C)C=1SC1=C(I)C=C2OCOC2=C1 |
| Hazard Information | Back Directory | [Uses]
Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease. |
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