| Identification | Back Directory | [Name]
Lexiscan | [CAS]
875148-45-1 | [Synonyms]
Cvt 3146
Lexiscan
Regadenoson Hydrate
1-{6-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-2-yl}-N-methyl-1H-pyrazole-4-carboxamide hydrate | [Molecular Formula]
C15H20N8O6 | [MOL File]
875148-45-1.mol | [Molecular Weight]
408.38 |
| Hazard Information | Back Directory | [Uses]
Regadenoson hydrate (NSC 169186) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson hydrate also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS[1][2]. | [References]
[1] Trochu JN, et al. Selective A2A adenosine receptor agonist as a coronary vasodilator in conscious dogs: potential for use in myocardial perfusion imaging. J Cardiovasc Pharmacol. 2003 Jan;41(1):132-9. DOI:10.1097/00005344-200301000-00017
[2] Jackson S, et al. The effect of regadenoson-induced transient disruption of the blood-brain barrier on temozolomide delivery to normal rat brain. J Neurooncol. 2016 Feb;126(3):433-9. DOI:10.1007/s11060-015-1998-4 |
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| Company Name: |
Pharma Affiliates
|
| Tel: |
172-5066494 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList694812/0_EN.htm |
| Company Name: |
CarboMer, Inc.
|
| Tel: |
858 552 0992 |
| Website: |
www.carbomer.com |
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