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881177-99-7

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881177-99-7 Structure

881177-99-7 Structure
IdentificationBack Directory
[Name]

Sphingolactone-24
[CAS]

881177-99-7
[Synonyms]

Sphingolactone-24
L-erythro-Hexonic acid, 2,3,5-trideoxy-2-hexyl-5-[[(2E,4E)-1-oxo-2,4-hexadien-1-yl]amino]-, γ-lactone, (2ξ)-
[Molecular Formula]

C18H29NO4
[MOL File]

881177-99-7.mol
[Molecular Weight]

323.43
Chemical PropertiesBack Directory
[Boiling point ]

564.6±46.0 °C(Predicted)
[density ]

1.059±0.06 g/cm3(Predicted)
[form ]

White waxy solid.
[pka]

13.21±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

Sphingolactone-24 is a selective and irreversible inhibitor of neutral sphingomyelinase.
[in vivo]

Sphingolactone-24 (1 mg/kg; i.p.; 3 and 9 h thereafter LPS) reduces the severity of LPS-induced ALI and increases the survival rate of LPS-induced lung injury mice[1].

Animal Model:C3H/HeN breeder mice (LPS 10 mg/kg; intranasal instillation)[1]
Dosage:1 mg/kg
Administration:I.p.; 3 and 9 h thereafter LPS
Result:Improved survival and reduced the severity of LPS-induced acute lung injury (ALI).
881177-99-7 suppliers list
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Energy Chemical  
Telephone: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Company Name: DAYANG CHEM (HANGZHOU) CO.,LTD  
Telephone: +86-88938639 +86-17705817739
Website: www.dycnchem.com
Tags:881177-99-7 Related Product Information
881177-99-7 1609105-89-6 934841-30-2 1405-10-3 9001-87-0 63335-25-1