| Identification | Back Directory | [Name]
Sphingolactone-24 | [CAS]
881177-99-7 | [Synonyms]
Sphingolactone-24
L-erythro-Hexonic acid, 2,3,5-trideoxy-2-hexyl-5-[[(2E,4E)-1-oxo-2,4-hexadien-1-yl]amino]-, γ-lactone, (2ξ)- | [Molecular Formula]
C18H29NO4 | [MOL File]
881177-99-7.mol | [Molecular Weight]
323.43 |
| Hazard Information | Back Directory | [Uses]
Sphingolactone-24 is a selective and irreversible inhibitor of neutral sphingomyelinase. | [in vivo]
Sphingolactone-24 (1 mg/kg; i.p.; 3 and 9 h thereafter LPS) reduces the severity of LPS-induced ALI and increases the survival rate of LPS-induced lung injury mice[1]. | Animal Model: | C3H/HeN breeder mice (LPS 10 mg/kg; intranasal instillation)[1] | | Dosage: | 1 mg/kg | | Administration: | I.p.; 3 and 9 h thereafter LPS | | Result: | Improved survival and reduced the severity of LPS-induced acute lung injury (ALI). |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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