ChemicalBook--->CAS DataBase List--->882286-32-0

882286-32-0

882286-32-0 Structure

882286-32-0 Structure
IdentificationBack Directory
[Name]

TSPC
[CAS]

882286-32-0
[Synonyms]

3-(thiophen-2-ylsulfonyl)pyrazine-2-carbonitrile
[Molecular Formula]

C9H5N3O2S2
[MOL File]

882286-32-0.mol
[Molecular Weight]

251.28
Chemical PropertiesBack Directory
[Boiling point ]

523.5±50.0 °C(Predicted)
[density ]

1.61±0.1 g/cm3(Predicted)
[solubility ]

DMF: 3 mg/ml; DMSO: 3 mg/ml
[form ]

A solid
[pka]

-7.85±0.10(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

HUN86320, also known as TSPC (short for 3-(2-Thienylsulfonyl)pyrazine-2-carbonitrile) is a Glycogen Synthase Kinase-?3β Inhibitor (GSK-3β Inhibitor). HUN86320 was first described in patent WO 2006079057. This product has no formal name at the moment.
[Uses]

TSPC is a phytohormone gibberellin (GA) perception inhibitor with an IC50 value of 10 μM in vitro[1].
[References]

[1] Jung-Min Yoon, et al. Chemical screening of an inhibitor for gibberellin receptors based on a yeast two-hybrid system. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1096-8. DOI:10.1016/j.bmcl.2012.12.007
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