| Identification | Back Directory | [Name]
Transcainide | [CAS]
88296-62-2 | [Synonyms]
R-54718
Transcainide
rel-(1R*)-2β*-[4-[(2,6-Dimethylphenyl)carbamoyl]-4-(dimethylamino)piperidino]1β*-cyclohexanol
4-(dimethylamino)-N-(2,6-dimethylphenyl)-1-[(1R,2R)-2-hydroxycyclohexyl]piperidine-4-carboxamide
4-Piperidinecarboxamide, 4-(dimethylamino)-N-(2,6-dimethylphenyl)-1-[(1R,2R)-2-hydroxycyclohexyl]-,rel- | [Molecular Formula]
C22H35N3O2 | [MDL Number]
MFCD01701295 | [MOL File]
88296-62-2.mol | [Molecular Weight]
373.538 |
| Hazard Information | Back Directory | [Uses]
Transcainide (R 54718) is an orally active antiarrhythmic agent[1]. | [References]
[1] Zamponi GW, et al. Transcainide causes two modes of open-channel block with different voltage sensitivities in batrachotoxin-activated sodium channels. Biophys J. 1994 Sep;67(3):1028-39. doi: 10.1016/S0006-3495(94)80568-5. Erratum in: Biophys J 1995 Mar;68(3):1197. DOI:10.1016/S0006-3495(94)80568-5
[2] R Stroobandt, Evaluation of the efficacy and tolerance of the antiarrhythmic agent transcainide (R 54718). Eur J Clin Pharmacol. 1987;32(5):449-56. DOI:10.1007/BF00637668 |
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