| Identification | Back Directory | [Name]
Benzamide, 2-[2-(5-bromo-2-methoxyphenyl)ethyl]-N-[[[(1-ethyl-4-piperidinyl)methyl]amino]iminomethyl]-3-fluoro- | [CAS]
884538-31-2 | [Synonyms]
Benzamide, 2-[2-(5-bromo-2-methoxyphenyl)ethyl]-N-[[[(1-ethyl-4-piperidinyl)methyl]amino]iminomethyl]-3-fluoro- | [Molecular Formula]
C25H32BrFN4O2 | [MOL File]
884538-31-2.mol | [Molecular Weight]
519.45 |
| Hazard Information | Back Directory | [Description]
MPCI is a selective antagonist of melanocortin-4 receptor (MC4R). | [Uses]
MPCI is a cell-permeant MC4R-selective ligand with pharmacological chaperone activity. MPCI is a MC4R antagonist with a Ki value of 0.218 μM on HEK293 cells expressing hMC4R. MPCI can be used for the research of MC4R-deficient obesity[1]. | [References]
[1] René P, et al. Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity. J Pharmacol Exp Ther. 2010 Dec;335(3):520-32. DOI:10.1124/jpet.110.172098 |
|
|