| Identification | Back Directory | [Name]
(+)-Guaiacin | [CAS]
88547-66-4 | [Synonyms]
2-Naphthalenol, 5,6,7,8-tetrahydro-8-(4-hydroxy-3-methoxyphenyl)-3-methoxy-6,7-dimethyl-, (6R,7S,8S)-rel- | [Molecular Formula]
C20H24O4 | [MOL File]
88547-66-4.mol | [Molecular Weight]
328.4 |
| Chemical Properties | Back Directory | [Melting point ]
173-175 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
484.5±45.0 °C(Predicted) | [density ]
1.151±0.06 g/cm3(Predicted) | [pka]
10.08±0.35(Predicted) |
| Hazard Information | Back Directory | [Uses]
(+)-Guaiacin is a compound extracted of the bark of Machilus wangchiana Chun. (Lauraceae). (+)-Guaiacin shows potent in vitro activities against the release of β-glucuronidase in rat polymorphonuclear leukocytes (PMNs) induced by platelet-activating factor (PAF) [1]. | [Definition]
ChEBI: (+)-guaiacin is a lignan. It has a role as a metabolite. | [References]
[1] Cheng W, et al. Chemical constituents of the bark of Machilus wangchiana and their biological activities. J Nat Prod. 2009 Dec;72(12):2145-52. DOI:10.1021/np900504a |
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