| Identification | Back Directory | [Name]
5-cyano-furan-2-carboxylic acid (2,4-di-piperidin-1-yl-phenyl)-amide | [CAS]
885704-58-5 | [Synonyms]
c-Fms-IN-13
5-cyano-furan-2-carboxylic acid (2,4-di-piperidin-1-yl-phenyl)-amide | [Molecular Formula]
C22H26N4O2 | [MOL File]
885704-58-5.mol | [Molecular Weight]
378.47 |
| Chemical Properties | Back Directory | [Boiling point ]
531.8±50.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMSO : 31.25 mg/mL (82.57 mM; Need ultrasonic) | [form ]
Solid | [pka]
10.52±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
c-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor with an IC50 value of 17 nM. c-Fms-IN-13 can be used as an anti-inflammatory agent[1]. | [storage]
4°C, protect from light | [References]
[1] Illig CR, et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8. DOI:10.1016/j.bmcl.2008.01.059 |
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