| Identification | Back Directory | [Name]
PEG9-Tos | [CAS]
886469-23-4 | [Synonyms]
Peg9-ots
PEG9-Tos
Tos-PEG8-OH
OH-PEG8-Tos
HO-(CH2CH2O)8-Tos
23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricosyl 4-methylbenzenesulfonate
3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol, 1-(4-methylbenzenesulfonate) | [Molecular Formula]
C23H40O11S | [MDL Number]
MFCD26127806 | [MOL File]
886469-23-4.mol | [Molecular Weight]
524.62 |
| Hazard Information | Back Directory | [Description]
PEG9-Tos is a PEG linker containing a hydroxyl group with a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions. | [Uses]
PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6 |
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