ChemicalBook--->CAS DataBase List--->887148-69-8

887148-69-8

887148-69-8 Structure

887148-69-8 Structure
IdentificationBack Directory
[Name]

BenzaMide, N-[(1S)-1-cyano-2-[5-cyano-2-(trifluoroMethyl)phenoxy]-1-Methylethyl]-4-[(trifluoroMethyl)thio]-
[CAS]

887148-69-8
[Synonyms]

AAD1566
Monepantel
Monepantel-d5
(S)-Monepantel
BenzaMide, N-[(1S)-1-cyano-2-[5-cyano-2-(trifluoroMethyl)phenoxy]-1-Methylethyl]-4-[(trifluoroMethyl)thio]-
[Molecular Formula]

C20H13F6N3O2S
[MOL File]

887148-69-8.mol
[Molecular Weight]

473.39
Chemical PropertiesBack Directory
[Melting point ]

70-73°C
[Boiling point ]

554.7±50.0 °C(Predicted)
[density ]

1.46±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly)
[form ]

Solid
[pka]

10.11±0.46(Predicted)
[color ]

White to Off-White
[JECFA Number]

85
Hazard InformationBack Directory
[Uses]

Monepantel is a recently discovered anthelmitic used in the treatment of parasitic nematodes via stun or kill without damaging the host entity.
[Definition]

ChEBI: A carboxamide resulting from the formal condensation of the carboxy group of p-[(trifluoromethyl)sulfanyl]benzoic acid with the amino group of (2S)-2-amino-3-hydroxy-2-methylpropanenitrile in which the hydroxy group has been c nverted to the corresponding 5-cyano-2-(trifluoromethyl)phenyl ether. A broad-spectrum nematicide, it is used to control gastrointestinal roundworms in sheep and goats.
[in vivo]

Monepantel (10 μM) significantly increased all CYP-related activities and CYP3A24 mRNA in?sheep[4].

[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

BenzaMide, N-[(1S)-1-cyano-2-[5-cyano-2-(trifluoroMethyl)phenoxy]-1-Methylethyl]-4-[(trifluoroMethyl)thio]-(887148-69-8)1HNMR
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