| Identification | More | [Name]
2'-Deoxyinosine | [CAS]
890-38-0 | [Synonyms]
2'-DEOXYINOSINE
9-(2-DEOXY-BETA-D-RIBOFURANOSYL)HYPOXANTHINE
DEOXYINOSINE, 2'-
DI
2’-deoxy-inosin
Deoxyinosine
Hypoxanthine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-
9-(2-deoxy-β-d-ribofuranosyl)hypoxanthine
2'-Deoxy-D-inosine
9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
DEOXYINOSINE, 2'-(P)
2''-DEOXYINOSINE Crystalline
9-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydropurin-6-one
2-DEOXYINOSINE extrapure
9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Inosine, 2'-deoxy- | [EINECS(EC#)]
212-964-1 | [Molecular Formula]
C10H12N4O4 | [MDL Number]
MFCD00005762 | [Molecular Weight]
252.23 | [MOL File]
890-38-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline | [Melting point ]
250 °C
| [alpha ]
21 º (c=1, H2O 22 ºC) | [Boiling point ]
395.4°C (rough estimate) | [density ]
1.3402 (rough estimate) | [refractive index ]
-16 ° (C=1, H2O) | [storage temp. ]
−20°C
| [solubility ]
DMSO (Slightly), Waterh (Slightly) | [form ]
Powder | [pka]
8.92±0.70(Predicted) | [color ]
White to Off-white | [biological source]
synthetic (organic) | [Water Solubility ]
8.33g/L(25.02 ºC) | [BRN ]
33517 | [InChI]
InChI=1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1 | [InChIKey]
VGONTNSXDCQUGY-RRKCRQDMSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)O)N=C2)C[C@@H]1O | [CAS DataBase Reference]
890-38-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Inosine, 2'-deoxy-(890-38-0) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
10-23 | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline | [Uses]
An Inosine (I661000) analog with hypotensive activity. An impurity of the antiviral drug 2’,3’-Dideoxyinosine (D440950). | [Definition]
ChEBI: 2'-deoxyinosine is a purine 2'-deoxyribonucleoside that is inosine in which the hydroxy group at position 2' is replaced by a hydrogen. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, a plant metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2'-deoxy-D-ribonucleoside and a purine 2'-deoxyribonucleoside. It is functionally related to an inosine. | [Biochem/physiol Actions]
2′-Deoxyinosine is a nucleoside form of hypoxanthine. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinosine is formed from nitrosative deamination by N2O3. | [Purification Methods]
2'-Deoxyinosine [890-38-0] M 252.2, m 206o(dec), 218-220o(dec), [ ] D25 -21o (c 2, N ] D -21o (c 1, H 2O), pKEst(1) ~ 8.9, pKEst(2) ~ 12.4. Purify 2'-deoxyinosine by recrystallisation from H2O. [Brown & Lythgoe J Chem Soc 1990 1950, UV: MacNutt Biochem J 50 384 1952, Beilstein 26 III/IV 2086.] |
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