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890409-87-7

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890409-87-7 Structure

890409-87-7 Structure
IdentificationBack Directory
[Name]

3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate
[CAS]

890409-87-7
[Synonyms]

NO2-SPP-sulfo-Me
3-(Methylsulfonyl)-2,5-dioxopyrrolidin-1-yl 4-((5-nitropyridin-2-yl)disulfanyl)pentanoate
[Molecular Formula]

C15H17N3O8S3
[MDL Number]

MFCD20226789
[MOL File]

890409-87-7.mol
[Molecular Weight]

463.51
Chemical PropertiesBack Directory
[Boiling point ]

687.5±65.0 °C(Predicted)
[density ]

1.59±0.1 g/cm3(Predicted)
[pka]

-2.22±0.29(Predicted)
Hazard InformationBack Directory
[Uses]

NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC)[1].
[IC 50]

Disulfide Cleavable Linker; Cleavable Linker
[References]

[1] Robert J. Lutz, et al.Methods for decreasing ocular toxicity of antibody drug conjugates. WO2012138749A1.
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