| Identification | Back Directory | [Name]
2,5-Dioxopyrrolidin-1-yl 4-methyl-4-((5-nitropyridin-2-yl)disulfanyl)pentanoate | [CAS]
663598-98-9 | [Synonyms]
NO2-SPDMV
2,5-Dioxopyrrolidin-1-yl 4-methyl-4-((5-nitropyridin-2-yl)disulfanyl)pentanoate | [Molecular Formula]
C15H17N3O6S2 | [MDL Number]
MFCD20228009 | [MOL File]
663598-98-9.mol | [Molecular Weight]
399.442 |
| Hazard Information | Back Directory | [Uses]
NO2-SPDMV is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Disulfide Cleavable Linker; Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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