| Identification | Back Directory | [Name]
BAMB-4 | [CAS]
891025-25-5 | [Synonyms]
BAMB-4
CS-1193
ITPKA-IN-C14
BAMB-4
(ITPKA-IN-C14)
ITPKA-IN-C14;BAMB-4;BAMB4;BAMB 4
Benzamide, N-1,2-benzisoxazol-3-yl-4-methyl- | [Molecular Formula]
C15H12N2O2 | [MOL File]
891025-25-5.mol | [Molecular Weight]
252.27 |
| Chemical Properties | Back Directory | [Boiling point ]
360.3±25.0 °C(Predicted) | [density ]
1.295±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
≥ 7.8mg/mL in DMSO | [form ]
Solid | [pka]
10.94±0.43(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
BAMB-4 (ITPKA-IN-C14) is a specific and membrane-permeable ITPKA inhibitor. BAMB-4 has high stability and membrane permeability and against the inositol-1,4,5-trisphosphate (InsP3) kinase activity of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA) with an IC50 value of 20 μM. BAMB-4 can be used for the research of metastasis of lung cancer[1]. | [storage]
Store at -20°C | [References]
[1] Dominik Schr?der, et al. Identification of a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A. Biochem Biophys Res Commun DOI:10.1016/j.bbrc.2013.08.053 |
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| Company Name: |
SPIRO PHARMA
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| Telephone: |
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| Website: |
www.spiropharma.com.cn |
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