ChemicalBook--->CAS DataBase List--->891025-25-5

891025-25-5

891025-25-5 Structure

891025-25-5 Structure
IdentificationBack Directory
[Name]

BAMB-4
[CAS]

891025-25-5
[Synonyms]

BAMB-4
CS-1193
ITPKA-IN-C14
BAMB-4 (ITPKA-IN-C14)
ITPKA-IN-C14;BAMB-4;BAMB4;BAMB 4
Benzamide, N-1,2-benzisoxazol-3-yl-4-methyl-
[Molecular Formula]

C15H12N2O2
[MOL File]

891025-25-5.mol
[Molecular Weight]

252.27
Chemical PropertiesBack Directory
[Boiling point ]

360.3±25.0 °C(Predicted)
[density ]

1.295±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

≥ 7.8mg/mL in DMSO
[form ]

Solid
[pka]

10.94±0.43(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

BAMB-4 (ITPKA-IN-C14) is a specific and membrane-permeable ITPKA inhibitor. BAMB-4 has high stability and membrane permeability and against the inositol-1,4,5-trisphosphate (InsP3) kinase activity of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA) with an IC50 value of 20 μM. BAMB-4 can be used for the research of metastasis of lung cancer[1].
[storage]

Store at -20°C
[References]

[1] Dominik Schr?der, et al. Identification of a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A. Biochem Biophys Res Commun DOI:10.1016/j.bbrc.2013.08.053
Spectrum DetailBack Directory
[Spectrum Detail]

BAMB-4(891025-25-5)1HNMR
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