| Identification | Back Directory | [Name]
N-(3-methoxyphenyl)-2-methyl-1-propionylindoline-5-sulfonamide | [CAS]
901008-62-6 | [Synonyms]
VU625
VU-625
VU 625
VU007625
VU-007625
VU 007625
N-(3-methoxyphenyl)-2-methyl-1-propionylindoline-5-sulfonamide | [Molecular Formula]
C19H22N2O4S | [MOL File]
901008-62-6.mol | [Molecular Weight]
374.45 |
| Hazard Information | Back Directory | [Description]
VU625 is a potent and selective inhibitor of aedes aegypti inward rectifier potassium channels. | [Uses]
VU625 is an inhibitor for potassium channel, that selectively inhibits mosquito Aedes aegypti inward rectifier potassium channel 1 (AeKir), with IC50 of 96.8 nM in HEK293 cell. VU625 can be used in development of insecticide[1]. | [References]
[1] Raphemot R, et al., Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels. PLoS One. 2014 Nov 6;9(11):e110772. DOI:10.1371/journal.pone.0110772 |
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