| Identification | Back Directory | [Name]
Alkyne NHS ester (hexynoic acid NHS ester) | [CAS]
906564-59-8 | [Synonyms]
5-Hexynoic NHS ester
Propargyl-C2-NHS ester
5-Hexynoic acid NHS ester
N-succinimidyl 5-hexynoate
2,5-dioxopyrrolidin-1-yl hex-5-ynoate
Alkyne NHS ester (hexynoic acid NHS ester)
5-Hexynoic acid 2,5-dioxo-1-pyrrolidinyl ester
hex-5-ynoic acid 2,5-dioxo-pyrrolidin-1-yl ester | [Molecular Formula]
C10H11NO4 | [MDL Number]
MFCD28898858 | [MOL File]
906564-59-8.mol | [Molecular Weight]
209.2 |
| Chemical Properties | Back Directory | [storage temp. ]
Storage temp. -20°C | [solubility ]
good in organic solvents (DMF, DMSO, DCM) | [form ]
Liquid | [color ]
Colorless to light yellow | [Appearance]
yellowish oil or off white crystals |
| Hazard Information | Back Directory | [Description]
5-Hexynoic Acid-NHS Ester contains a propargyl group and an NHS ester group. This reagent is an amine reactive reagent for derivatizing peptides, antibodies, amine coated surfaces etc. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. | [Uses]
5-Hexynoic NHS Ester is a nonclaevable linker for antibody-drug-conjugation. 5-Hexynoic NHS Ester is used in the preparation of biomimetic G-quartet compounds for detection, imaging and purification of G-quartet nucleic acids. | [IC 50]
Non-cleavable Linker |
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