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911211-69-3

911211-69-3 Structure

911211-69-3 Structure
IdentificationBack Directory
[Name]

Benzamide, 2-chloro-N-[4-[6-[(cyclopropylcarbonyl)amino]-1H-benzimidazol-2-yl]phenyl]-
[CAS]

911211-69-3
[Synonyms]

Benzamide, 2-chloro-N-[4-[6-[(cyclopropylcarbonyl)amino]-1H-benzimidazol-2-yl]phenyl]-
[Molecular Formula]

C24H19ClN4O2
[MOL File]

911211-69-3.mol
[Molecular Weight]

430.89
Chemical PropertiesBack Directory
[density ]

1.467±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

10.72±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

NR2E3 agonist 1 (Compound 11a) is a small molecule agonist of the photoreceptor-specific nuclear receptor (NR2E3) with an EC50 value of less than 200 nM. NR2E3 agonist 1 can be used in retinitis pigmentosa research[1].
[References]

[1] Wolkenberg SE, et al. Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5001-4. DOI:10.1016/j.bmcl.2006.07.056
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