| Identification | More | [Name]
Methyl 2-oxoacetate | [CAS]
922-68-9 | [Synonyms]
2-(2-METHOXPHENOXYL) ETHYLAMINE HCL
2-(2-METHOXPHENOXYL)ETHYLAMINE MONOHYDROCHLORIDE
2-(2-METHOXYPHENOXY)ETHANAMINE HCL
2-(2-METHOXYPHENOXY)ETHYLAMINE HCL
2-(2-METHOXYPHENOXY)ETHYLAMINE HYDROCHLORIDE
2-(METHOXY PHENOXY)ETHYLAMINE HYDROCHLORIDE
GAME
GLYOXYLIC ACID METHYL ESTER
METHYL GLYOXYLATE
Acetic acid, oxo-, methyl ester
Methyl oxoacetate
oxo-aceticacimethylester
2-(2-methyoxy phenoxy) ethylamine HCL
L-MENTHYL GLYOXYLATE HYDRATE ( MGH) STAGE I
2-(2-Methoxphenoxyl)ethylamine
Methyl 2-oxoacetate
2-Oxoacetic acid methyl ester
Glyoxalic acid methyl ester
Oxoacetic acid methyl ester | [EINECS(EC#)]
213-084-0 | [Molecular Formula]
C3H4O3 | [MDL Number]
MFCD01631120 | [Molecular Weight]
88.06 | [MOL File]
922-68-9.mol |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . |
| Hazard Information | Back Directory | [Uses]
Methyl Glyoxylate is a useful compound for preparation of pyridine and quinoline derivatives. | [Preparation]
Preparative Methods of Methyl 2-oxoacetate: efficient methods include oxidative cleavage of tartrate diesters, ozonolysis of
maleate/fumarate derivatives, exchange reaction between appropriate dialkoxyacetate and glyoxylic acid,
and NaOAc-catalyzed elimination of nitrite ion from nitrate esters.[1] | [General Description]
Methyl Glyoxylate is a two-carbon synthon utilized in electrocyclic processes (Diels-Alder reaction, ene reactions), various
condensations (Mannich, aldol, Wittig, Prins, acyloin), carbinolamine formation, and Friedel-Crafts
reactions. | [storage]
Methyl 2-oxoacetate stores under N2 in a refrigerator due to their tendency to form a
monohydrate and/or polymerize. | [References]
1. (a) Wolf, F. J.; Weijland, J. OSC 1963, 4, 124. (b) Jung, M. E.; Shishido, K.; Davis, L. H. JOC 1982, 47, 891. (c)
Blake, J.; Tretter, J. R.; Juhasz, G. J.; Bonthrone, W.; Rappoport, H. JACS 1966, 88, 4061. (d) Haggerty, J. G.; Kelly,
T. R.; Schmidt, T. E. S 1972, 544. Hook, J. M. SC 1984, 14, 83. (e) Kornblum, N.; Frazier, H. W. JACS 1966, 88, 865. |
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