| Identification | Back Directory | [Name]
2',3'-DIDEOXY-3'-FLUORO-GUANOSINE | [CAS]
92562-88-4 | [Synonyms]
MIV 210
Lagociclovir
Lagociclovir(MIV-210)
3'-fluoro-2',3'-dideoxyguanosine
2',3'-DIDEOXY-3'-FLUORO-GUANOSINE
Guanosine, 2',3'-dideoxy-3'-fluoro- | [Molecular Formula]
C10H12FN5O3 | [MDL Number]
MFCD00882020 | [MOL File]
92562-88-4.mol | [Molecular Weight]
269.23 |
| Chemical Properties | Back Directory | [Melting point ]
253-255 °C (decomp) | [Boiling point ]
633.5±65.0 °C(Predicted) | [density ]
2.01±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
14.44±0.10(Predicted) | [InChI]
InChI=1S/C10H12FN5O3/c11-4-1-6(19-5(4)2-17)16-3-13-7-8(16)14-10(12)15-9(7)18/h3-6,17H,1-2H2,(H3,12,14,15,18)/t4-,5+,6+/m0/s1 | [InChIKey]
RTJUXLYUUDBAJN-KVQBGUIXSA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)C[C@@H]1F |
| Hazard Information | Back Directory | [Uses]
Lagociclovir (FLG) is a nucleoside analogue that inhibits wild-type hepatitis B virus (HBV) replication in a human hepatoma cell line permanently expressing HBV[1]. | [References]
[1] Jacquard AC, et al. In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine. Antimicrob Agents Chemother. 2006 Mar;50(3):955-61. DOI:10.1128/AAC.50.3.955-961.2006 |
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| Company Name: |
Musechem
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| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
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