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93361-66-1

93361-66-1 Structure

93361-66-1 Structure
IdentificationBack Directory
[Name]

(2S)-2-[2-[[(1S)-1-carboxy-2-(3H-imidazol-4-yl)ethyl]amino]ethylamino] -5-(diaminomethylideneamino)pentanoic acid
[CAS]

93361-66-1
[Synonyms]

histargin
Nα-[2-[[(S)-4-Guanidino-1-carboxybutyl]amino]ethyl]-L-histidine
(2S)-2-[2-[[(1S)-1-carboxy-2-(3H-imidazol-4-yl)ethyl]amino]ethylamino] -5-(diaminomethylideneamino)pentanoic acid
[Molecular Formula]

C14H25N7O4
[MOL File]

93361-66-1.mol
Hazard InformationBack Directory
[Description]

Histargin is an enzyme inhibitor isolated from Streptomyces roseoviridis.
[Uses]

Histargin is a carboxypeptidase B inhibitor with IC50 of 17 μg/ml and > 100 μg/ml aganist Carboxypeptidase B and Carboxypeptidase A, respectively. Histargin can be produced by actinomycetes[1].
[References]

[1] Umezawa H, et al. Histargin, a new inhibitor of carboxypeptidase B, produced by actinomycetes. J Antibiot (Tokyo). 1984 Sep;37(9):1088-90. DOI:10.7164/antibiotics.37.1088
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