| Identification | Back Directory | [Name]
8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one 4-methylbenzenesulfonate (salt) | [CAS]
937169-00-1 | [Synonyms]
Dilmapimod tosylate
8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one 4-methylbenzenesulfonate (salt) | [EINECS(EC#)]
629-888-3 | [Molecular Formula]
C30H27F3N4O6S | [MOL File]
937169-00-1.mol | [Molecular Weight]
628.619 |
| Hazard Information | Back Directory | [Uses]
Dilmapimod tosylate is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease. | [References]
[1] Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50(1):94-100. DOI:10.1177/0091270009347873 |
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