| Identification | Back Directory | [Name]
AZD2624 | [CAS]
941690-55-7 | [Synonyms]
AZD2624
AZD4901
MLE-4901
Pavinetant
Pavinetant (MLE-4901)
3-(methanesulfonamido)-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
4-Quinolinecarboxamide, 3-[(methylsulfonyl)amino]-2-phenyl-N-[(1S)-1-phenylpropyl]- | [Molecular Formula]
C26H25N3O3S | [MOL File]
941690-55-7.mol | [Molecular Weight]
459.56 |
| Chemical Properties | Back Directory | [density ]
1.285±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:3): 0.25mg/mL; DMSO: 20mg/mL | [form ]
A crystalline solid | [pka]
1.35±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MLE-4901, is a neurokinin-3 receptor (NK3R) antagonist. | [Definition]
ChEBI:Pavinetant is a member of the class of quinolines that is the amide obtained by formal condensation of the carboxy group of 3-[(methanesulfonyl)amino]-2-phenylquinoline-4-carboxylic acid with the amino group of (1S)-1-phenylpropan-1-amine. A neurokinin-3 receptor antagonist that has been trialled as a potential drug for treatment of schizophrenia and menopausal symptoms. It has a role as a neurokinin-3 receptor antagonist and an antipsychotic agent. It is a member of quinolines, a secondary carboxamide, a sulfonamide and an aromatic amide. | [IC 50]
NK3 | [storage]
Store at -20°C |
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| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310; |
| Website: |
https://www.weikeqi-biotech.com/ |
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