| Identification | Back Directory | [Name]
Ulixertinib | [CAS]
949904-48-7 | [Synonyms]
3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide
3-((1R,3S,5S)-8-(2-((S)-N-(CYCLOHEXYLMETHYL)-2,3-DIHYDROXYPROPANAMIDO)ETHYL)-8-AZABICYCLO[3.2.1]OCTAN-3-YL)BENZAMIDE
Benzamide, 3-[(3-endo)-8-[2-[(cyclohexylmethyl)[(2S)-2,3-dihydroxy-1-oxopropyl]amino]ethyl]-8-azabicyclo[3.2.1]oct-3-yl]- | [Molecular Formula]
C26H39N3O4 | [MDL Number]
MFCD28502065 | [MOL File]
949904-48-7.mol | [Molecular Weight]
457.62 |
| Hazard Information | Back Directory | [Uses]
Axelopran (TD-1211) is an opioid receptor antagonist with pKi values of 9.8, 8.8 and 9.9 for human recombinant μ and δ receptors and guinea pig κ receptor, respectively. | [IC 50]
guinea pig κ-opioid receptor: 9.9 (pKi); human μ-opioid receptor: 9.8 (pKi); δ Opioid Receptor/DOR: 8.8 (pKi) | [References]
[1] Tsuruda PR, et al., The in vitro pharmacological profile of TD-1211, a neutral opioid receptor antagonist. Naunyn Schmiedebergs Arch Pharmacol. 2013 Jun;386(6):479-91. DOI:10.1007/s00210-013-0850-7 |
|
| Company Name: |
AstaTech, Inc
|
| Tel: |
(215) 785 3197 |
| Website: |
www.astatechinc.com |
|