Identification | Back Directory | [Name]
YADANZIOLIDE-C | [CAS]
95258-12-1 | [Synonyms]
YADANZIOLIDE-C (+)-13,20-Epoxy-1α,11β,12α,14,15β-pentahydroxypicras-3-ene-2,16-dione (+)-13,20-Epoxy-1α,11β,12α,14,15β-pentahydroxypicrasa-3-ene-2,16-dione Picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1α,11β,12α,15β)- (9CI) | [Molecular Formula]
C20H26O9 | [MDL Number]
MFCD34568099 | [MOL File]
95258-12-1.mol | [Molecular Weight]
410.42 |
Hazard Information | Back Directory | [Uses]
Yadanziolide C is a quassinoid with antiproliferative and differentiation-inducing properties in promyelocytic HL-60 cells[1]. | [References]
[1] L Luyengi, et al. A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL-60 promyelocytic leukemia cells. Phytochemistry. 1996 Sep;43(2):409-12. DOI:10.1016/0031-9422(96)00258-0 [2] E Mata-Greenwood, et al. Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture. Nat Prod. DOI:10.1021/np010212p |
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