| Identification | More | [Name]
2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt | [CAS]
979-88-4 | [Synonyms]
2,2'-BICINCHONINIC ACID DISODIUM SALT
2,2'-BIQUINOLINE-4,4'-DICARBOXYLIC ACID DISODIUM SALT
2,2'-BIQUINOLINE-4,4'-DICARBOXYLIC ACID DISODIUM SALT TRIHYDRATE
4,4'-DICARBOXY-2,2'-BIQUINOLINE DISODIUM SALT
4,4'-DICARBOXY-2,2'-BIQUINOLINE, SODIUM SALT
BCA
BCA DISODIUM SALT
BICINCHONINIC ACID DISODIUM SALT
BICINCHONINIC ACID DISODIUM SALT HYDRATE
DI-SODIUM 2,2'-BICINCHONINATE
DISODIUM 2,2'-BIQUINOLINE-4,4'-DICARBOXYLATE
SODIUM BICINCHONINATE,4,4'-DICARBOXY-2,2'-BIQUINOLINE
2,2’-biquinoline-4,4’-dicarboxylicaciddisodiumsalt2h2o
SodiumBicinchoniate
SodiumBicinchoninate
2,2'-BIQUINOLINE-4,4'-DICARBOXYLIC ACID DISODIUM SALT 2-HYDRATE
4 4''-DICARBOXY-2 2''-BIQUINOLINE DISODIUM BCA
4,4'-Dicarboxy-2,2'-biquinoline disodium salt>98%
Bicinchoninic acid disodium salt, BCA disodium salt
4,4μ-Dicarboxy-2,2μ-biquinoline disodium salt, BCA, Disodium 2,2μ-biquinoline-4,4μ-dicarboxylate, 2,2μ-Biquinoline-4,4μ-dicarboxylic acid disodium salt | [EINECS(EC#)]
629-761-2 | [Molecular Formula]
C20H11N2Na2O4 | [MDL Number]
MFCD00037500 | [Molecular Weight]
389.29 | [MOL File]
979-88-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
300℃ | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
0.5% sodium bicarbonate: soluble50mg/mL | [form ]
Powder/Chunks | [color ]
white to light yellow | [Water Solubility ]
Soluble in water. | [Detection Methods]
HPLC | [Stability:]
Hygrscopic | [Major Application]
diagnostic assay manufacturing
hematology
histology | [InChI]
InChI=1S/C20H12N2O4.Na.H/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;/h1-10H,(H,23,24)(H,25,26);; | [InChIKey]
AUPXFICLXPLHBB-UHFFFAOYSA-L | [SMILES]
C(C1=CC(C2=NC3=CC=CC=C3C(C(=O)O)=C2)=NC2=CC=CC=C12)(=O)O.[NaH] | [CAS DataBase Reference]
979-88-4(CAS DataBase Reference) | [EPA Substance Registry System]
979-88-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37:Irritating to eyes and respiratory system .
R42:May cause sensitization by inhalation.
R36/38:Irritating to eyes and skin .
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2 |
| Hazard Information | Back Directory | [Description]
2,2’-Biquinoline-4,4’-dicarboxylic acid (BCA) is a colorimetric reagent for the detection of copper (Cu+).1,2 BCA and Cu+ form a stable 2:1 complex that has an absorbance maximum at 562 nm.1 It is commonly used as a reagent in the colorimetric BCA protein quantitation assay in which Cu2+ is converted to Cu+ as a function of protein concentration under alkaline conditions.1,3 | [Chemical Properties]
White to light yellow powder | [Uses]
For determination of Cu and protein assays.Bicinchoninic acid disodium salt is useful for the determination of copper. It is also used for the determination of protein concentration. | [Application]
2,2'-Bicinchoninic Acid Disodium Salt is a photometric reagent for protein assay. It is used for determination of reducing sugar and protein via Cu(I). Also a specific reagent for Cu(I) with sensitivity similar to that of neocuproin. | [Biochem/physiol Actions]
Bicinchoninic acid is used for the determination of protein concentration. It is responsible for the making of intense purple complex with cuprous ion (Cu+), in presence of alkaline conditions. The amount of Cu+ is in relation with the protein concentration. | [References]
[1] P.K. SMITH. Measurement of protein using bicinchoninic acid[J]. Analytical biochemistry, 1985, 150 1: Pages 76-85. DOI: 10.1016/0003-2697(85)90442-7
[2] BRENNER A.J. Harris E D. A Quantitative Test for Copper Using Bicinchoninic Acid[J]. Analytical biochemistry, 1995, 226 1: Pages 80-84. DOI: 10.1006/abio.1995.1194
[3] WALKER J M. The bicinchoninic acid (BCA) assay for protein quantitation.[J]. Methods in molecular biology, 1994, 32: 5-8. DOI: 10.1385/0-89603-268-x:5 |
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