| Identification | More | [Name]
Difloxacin | [CAS]
98106-17-3 | [Synonyms]
DIFLOXACIN
-1-piperazinyl)-4-oxo-
3-quinolinecarboxylicacid,1,4-dihydro-6-fluoro-1-(4-fluorophenyl)-7-(4-methyl
a56619
6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride Salt
Difloxacin Hydrochloride Salt
6-Fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
DIFLOXACINHCL/MESYLATE
6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methylpiperazin-1-yl)-4-oxo-3-quinolinecarboxylic acid
6-Fluoro-1-(4-fluorophenyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | [Molecular Formula]
C21H19F2N3O3 | [MDL Number]
MFCD00865975 | [Molecular Weight]
399.39 | [MOL File]
98106-17-3.mol |
| Questions And Answer | Back Directory | [Description]
Difloxacin (INN) is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine,it has broad-spectrum, concentration dependent, bactericidal activity; however, its efficacy is not as good as enrofloxacin or pradofloxacin. | [Mechanism of action]
Difloxacin mainly acts on bacterial deoxyribonucleic acid (DNA) helicase, inhibiting DNA replication and transcription, thereby affecting the normal shape and function of DNA to achieve bactericidal purposes. |
| Chemical Properties | Back Directory | [Appearance]
Whtie-Cream to Yellowish Crystalline Powder | [Melting point ]
279-282 °C(Solv: chloroform (67-66-3); ethanol (64-17-5)) | [Boiling point ]
595.5±50.0 °C(Predicted) | [density ]
1.409±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
6.17±0.41(Predicted) | [color ]
White to Pale Yellow | [Usage]
A fluoroquinolone antibacterial structurally related to norfloxacin | [CAS DataBase Reference]
98106-17-3(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Physical properties]
Whtie-Cream to Yellowish Crystalline Powder | [Uses]
Difloxacin is a fluoroquinolone antibacterial structurally related to norfloxacin. | [Definition]
ChEBI: A quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usuall
as the monohydrochloride salt) for the treatment of bacterial infections in dogs. |
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