| Identification | Back Directory | [Name]
L 651142 | [CAS]
99046-40-9 | [Synonyms]
L651
L-651
L 651
L 651142
4-[(E)-[5-methoxy-3-(2-methoxyethyl)-2-methylinden-1-ylidene]methyl]benzenesulfonamide
4-[[(1E)-5-Methoxy-3-(2-methoxyethyl)-2-methyl-1H-inden-1-ylidene]methyl]benzenesulfonamide | [Molecular Formula]
C21H23NO4S | [MOL File]
99046-40-9.mol |
| Hazard Information | Back Directory | [Description]
L 651142 is a weak inhibitor of platelet activating factor receptor binding to polymorphonuclear leukocytes. | [Uses]
L 651142 is a weak platelet activating factor (PAF) receptor antagonist. L 651142 inhibits the binding of [3H]PAF to rabbit platelet, human platelet or human lung membranes with Kis of 0.839 μM, 1.82 μM, 3.64 μM, respectively[1]. | [References]
[1] S B Hwang, et al. Species difference in the specific receptors of platelet activating factor. Biochem Pharmacol. 1986 Dec 15;35(24):4511-8. DOI:10.1016/0006-2952(86)90772-0 |
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