| Identification | Back Directory | [Name]
15-hexadecynoic acid | [CAS]
99208-90-9 | [Synonyms]
Boc-β-homoarginine
15-hexadecynoic acid
Palmitic Acid Alkyne
hexadec-15-ynoic acid
Alkynyl Palmitic Acid
Palmitic acid (15-yne)
15-hexadecyn-1-oic acid
15-HEXADECYNOIC ACID;PALMITIC ACID (15-YNE) | [Molecular Formula]
C16H28O2 | [MDL Number]
MFCD22124928 | [MOL File]
99208-90-9.mol | [Molecular Weight]
252.39 |
| Chemical Properties | Back Directory | [Melting point ]
59.1°C (estimate) | [Boiling point ]
409.64°C (rough estimate) | [density ]
0.9310 (rough estimate) | [refractive index ]
1.4217 (estimate) | [storage temp. ]
-20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.15 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Alkynyl palmitic acid can be used to identify and characterize the post-translational S-palmitoylation of proteins with Click Chemistry. | [Uses]
15-hexadecynoic acid is a form of palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in linking reactions, known as click chemistry; this chemistry is characterized by high dependability and specificity of the azide-alkyne bioconjugation reactions. The use of palmitic acid alkyne and related lipids in isolating palmitoylated proteins has been described.
| [Biochem/physiol Actions]
Alkynyl palmitic acid (aPA) is a modified palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′. The click chemistry reactions are rapid, convenient, versatile and regiospecific. They are easy to purify. aPA can be used for isolating palmitoylated proteins. | [IC 50]
Alkyl-Chain |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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Alfa Chemistry
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https://www.alfa-chemistry.com |
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