| Identification | More | [Name]
17-OCTADECYNOIC ACID | [CAS]
34450-18-5 | [Synonyms]
ODYA
17-ODA
17-ODYA
17-OCTADECYNOIC ACID
Alkynyl Stearic Acid
DZIILFGADWDKMF-UHFFFAOYSA-N
17-ODYA (17-Octadecynoic acid)
17-OCTADECYNOIC ACID \ CYTOCHROME P450 E | [Molecular Formula]
C18H32O2 | [MDL Number]
MFCD00077382 | [Molecular Weight]
280.45 | [MOL File]
34450-18-5.mol |
| Chemical Properties | Back Directory | [Boiling point ]
400.8±18.0 °C(Predicted) | [density ]
0.922±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Soluble to 50 mM in ethanol and to 100 mM in DMSO | [form ]
White solid. | [pka]
4.78±0.10(Predicted) | [color ]
White to off-white | [InChI]
1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h1H,3-17H2,(H,19,20) | [InChIKey]
DZIILFGADWDKMF-UHFFFAOYSA-N | [SMILES]
C#CCCCCCCCCCCCCCCCC(O)=O | [CAS DataBase Reference]
34450-18-5(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Alkynyl stearic acid can be used to identify and characterize the post-translational acylation of proteins with powerful Click Chemistry. | [Uses]
17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of LTB4 ω-oxidase. | [Definition]
ChEBI: Octadec-17-ynoic acid is an acetylenic fatty acid that is octadecanoi acid (stearic acid) which has been doubly dehydrogenated at positions 17 and 18 to give the corresponding alkynoic acid. It has a role as a P450 inhibitor, an EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor and an EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor. It is a long-chain fatty acid, an acetylenic fatty acid, a terminal acetylenic compound and a monounsaturated fatty acid. | [Biological Activity]
Potent suicide inhibitor of LTB 4 ω -hydroxylase. | [Biochem/physiol Actions]
17-Octadecynoic acid (7-ODYA) is an irreversible inhibitor of cytochrome P450 isozymes, that participates in long-chain fatty acid metabolism. | [storage]
Store at -20°C |
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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