| Identification | More | [Name]
Levodropropizine | [CAS]
99291-25-5 | [Synonyms]
(S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
Levodropropizine
(2S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
Danka
l-Dropropizine
Levotuss
LVDP
Rapitux | [EINECS(EC#)]
640-087-8 | [Molecular Formula]
C13H20N2O2 | [MDL Number]
MFCD00866852 | [Molecular Weight]
236.31 | [MOL File]
99291-25-5.mol |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
98-100°C | [Boiling point ]
412.7±34.0 °C(Predicted) | [density ]
1.168±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Slightly soluble in water, freely soluble in dilute acetic acid and in methanol, slightly soluble in ethanol (96 per cent). | [form ]
neat | [pka]
14.21±0.20(Predicted) | [color ]
White to Almost white | [Usage]
S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive | [Major Application]
pharmaceutical (small molecule) | [InChI]
InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2/t13-/m0/s1 | [InChIKey]
PTVWPYVOOKLBCG-ZDUSSCGKSA-N | [SMILES]
C(O)[C@@H](O)CN1CCN(C2=CC=CC=C2)CC1 | [CAS DataBase Reference]
99291-25-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [HS Code ]
2933.59.5300 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Cough Suppressant | [Uses]
S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive | [Definition]
ChEBI: A member of the class of N-arylpiperazines that is N-phenylpiperazine in which the amino hydrogen is replaced by a 2,3-dihydroxypropyl group (the S-enantiomer). A peripherally acting antitussive drug t
at is used as an alternative to opioids. | [Biological Activity]
Levodropropizine has affinity for H1-histaminic and α-adrenergic receptors. Cough suppressant. |
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