1112994-35-0
中文名称
化合物 T28285
英文名称
P 2281
CAS
1112994-35-0
分子式
C9H8ClN3O
分子量
209.63
MOL 文件
1112994-35-0.mol
更新日期
2024/11/01 21:59:59
1112994-35-0 结构式
应用领域
用途一
P-2281 is a mTOR inhibitor and is efficacious in a murine model of human colitis. In the dextran sulfate sodium (DSS) model of colitis, macroscopic colon observations demonstrated that P2281 significantly inhibited DSS-induced weight loss, improved rectal bleeding index, decreased disease activity index, and reversed DSS-induced shortening of the colon.