134044-97-6
134044-97-6 结构式
基本信息
中文别名
化合物 T23615 英文别名
aciculatin4H-1-Benzopyran-4-one, 8-(2,6-dideoxy-β-D-ribo-hexopyranosyl)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-
所属类别
天然产物：黄酮类化合物物理化学性质
沸点686.245±55.00 °C(Press: 760.00 Torr)(predicted)
密度1.447±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
酸度系数(pKa)6.327±0.40(predicted)
LogP1.928 (est)
应用领域
用途一
Aciculatin, a natural compound extracted from the medicinal herb Chrysopogon aciculatus, shows potent anti-cancer potency. Aciculatin treatment induces cell cycle arrest and apoptosis via inhibition of MDM2 expression, thereby inducing p53 accumulation without significant DNA damage and genome toxicity.