1454885-45-0
1454885-45-0 结构式
物理化学性质
沸点502.7±50.0 °C(Predicted)
密度1.303±0.06 g/cm3(Predicted)
溶解度DMF: 25 mg/ml
DMSO: 25 mg/ml
Ethanol: 10 mg/ml
DMSO: 25 mg/ml
Ethanol: 10 mg/ml
酸度系数(pKa)9.20±0.15(Predicted)
应用领域
用途一
SP-8356 an anti-inflammatory synthetic verbenone derivative, is a potent, orally active cluster of differentiation 147 (CD147) inhibitor. SP-8356 inhibits CD147-cyclophilin A (CypA) interaction and reduces MMP-9 activity. SP-8356 exerts anti-breast cancer effects by inhibiting NF-κB signaling.