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1496712-39-0

中文名称 沙格列汀杂质15
英文名称 Saxagliptin Impurity 15
CAS 1496712-39-0
分子式 C18H27N3O3
分子量 333.43
MOL 文件 1496712-39-0.mol
更新日期 2024/04/28 11:58:01
1496712-39-0 结构式 1496712-39-0 结构式

基本信息

中文别名
沙格列汀杂质15
沙格列汀杂质15盐酸盐
沙格列汀杂质15 HCL
沙格列汀杂质BMS-554083对照品
沙格列汀杂质19(BMS-554083)
沙沙利汀杂质19(BMS-554083)
英文别名
Saxagliptin Amide Impurity
Saxagliptin Impurity 15 HCl
Saxagliptin Impurity 19(BMS-554083)
(1S,3S,5S)-2-((S)-2-amino-2-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carboxamide
2-Azabicyclo[3.1.0]hexane-3-carboxamide, 2-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3S,5S)-
Saxagliptin Amide ImpurityQ: What is Saxagliptin Amide Impurity Q: What is the CAS Number of Saxagliptin Amide Impurity Q: What is the storage condition of Saxagliptin Amide Impurity Q: What are the applications of Saxagliptin Amide Impurity
所属类别
分析化学:药典标准品和杂质标准品

物理化学性质

沸点603.4±40.0 °C(Predicted)
密度1.437±0.06 g/cm3(Predicted)
酸度系数(pKa)15.12±0.40(Predicted)

应用领域

用途一
3-Descarbonitrile 3-Acetamido Saxagliptin is a Saxagliptin (S143500) impurity, a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
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