1660143-42-9
中文名称
PR-059462
英文名称
(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
CAS
1660143-42-9
分子式
C40H57N5O6
分子量
703.91
MOL 文件
1660143-42-9.mol
更新日期
2025/05/09 09:33:22
1660143-42-9 结构式
基本信息
中文别名
卡非佐米杂质Y卡非佐米杂质11
卡非佐米杂质PR-059462
英文别名
PR-059462Kyprolis Impurity Y
Carfilzomib Impurity Y
Alkene Leucine Carfilzomib
(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
应用领域
用途一
(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxo-3-buten-1-yl]-L-phenylalaninamide is an impurity/intermediate in the preparation of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.