ChemicalBook--->CAS DataBase List--->1660143-42-9

1660143-42-9

1660143-42-9 Structure

1660143-42-9 Structure
IdentificationBack Directory
[Name]

(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
[CAS]

1660143-42-9
[Synonyms]

PR-059462
Kyprolis Impurity Y
Carfilzomib Impurity Y
Alkene Leucine Carfilzomib
(S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
[Molecular Formula]

C40H57N5O6
[MOL File]

1660143-42-9.mol
[Molecular Weight]

703.91
Hazard InformationBack Directory
[Uses]

(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-(2-methylpropyl)-2-oxo-3-buten-1-yl]-L-phenylalaninamide is an impurity/intermediate in the preparation of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
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