2062663-62-9
中文名称
AMINOOXY-PEG4-CH2CO2TBU
英文名称
Aminooxy-PEG4-CH2CO2tBu
CAS
2062663-62-9
分子式
C14H29NO7
分子量
323.38
MOL 文件
2062663-62-9.mol
更新日期
2023/02/20 14:06:15
2062663-62-9 结构式
基本信息
中文别名
氨基-四聚乙二醇 -TUB保护羧基 英文别名
Aminooxy-PEG4-CH2-BocAminooxy-PEG5-CH2CO2tBu
Aminooxy-PEG4-CH2CO2tBu
所属类别
催化剂及助剂：聚合物物理化学性质
沸点418.5±40.0 °C(Predicted)
密度1.082±0.06 g/cm3(Predicted)
酸度系数(pKa)4.21±0.70(Predicted)
InChIInChI=1S/C14H29NO7/c1-14(2,3)22-13(16)12-20-9-8-18-5-4-17-6-7-19-10-11-21-15/h4-12,15H2,1-3H3
InChIKeyYIWYEQPSYTYCHV-UHFFFAOYSA-N
SMILESC(OC(C)(C)C)(=O)COCCOCCOCCOCCON
应用领域
用途一
Aminooxy-PEG4-CH2CO2tBu is a PEG derivative containing an aminooxy group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The t-butyl protected carboxyl group can be hydrolyzed to form a free acid. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.