212118-77-9
212118-77-9 结构式
基本信息
中文别名
卢米奥绿色荧光含砷螺旋粘结剂/卢米奥绿色
2-[4,5-二(1,3,2-二硫杂砷戊环-2-基)-6-羟基-3-氧代-3H-氧杂蒽-9-基]苯甲酸
英文别名
FLASHFLASH-EDT2
LuMio Green
fluorescein bis-arsenide
FLUORESCEIN ARSENICAL HELIX BINDER
FLASH Fluorescein arsenical helix binder
4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-
所属类别
医药中间体：原料药中间体物理化学性质
储存条件Store at -20°C,protect from light
溶解度DMF: 15 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.09 mg/ml
形态结晶固体
颜色White to light yellow
应用领域
用途一
The Fluorescein Arsenical Hairpin Binder (FlAsH) method is presented for fluorescence labeling of proteins in living cells. Labeling proteins with the membrane-permeant fluorogenic biarsenical dye fluorescein arsenical hairpin binder-ethanedithiol (FlAsH-EDT2). The membrane-permeant fluorogenic biarsenicals FlAsH-EDT2 and ReAsH-EDT2 can be prepared in good yields by a straightforward two-step procedure from the inexpensive precursor dyes fluorescein and resorufin.常见问题列表
概述
荧光含砷螺旋粘结剂/卢米奥绿色 是一种蛋白质标记试剂。FlAsH-EDT2 也是一种可透过膜的荧光双砷化合物。FlAsH-EDT2 可以与 CCXXCC 基序和非特异性内源性富含半胱氨酸的蛋白质结合。FlAsH-EDT2 仅可用于标记那些以非常高水平表达的重组蛋白。