ChemicalBook--->CAS DataBase List--->212118-77-9

212118-77-9

212118-77-9 Structure

212118-77-9 Structure
IdentificationBack Directory
[Name]

FLASH
[CAS]

212118-77-9
[Synonyms]

FLASH
FLASH-EDT2
LuMio Green
fluorescein bis-arsenide
FLUORESCEIN ARSENICAL HELIX BINDER
FLASH Fluorescein arsenical helix binder
4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-
[Molecular Formula]

C24H18As2O5S4
[MDL Number]

MFCD07437941
[MOL File]

212118-77-9.mol
[Molecular Weight]

664.5
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C,protect from light
[solubility ]

DMF: 15 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.09 mg/ml
[form ]

A crystalline solid
[color ]

White to light yellow
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)
GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501
Hazard InformationBack Directory
[Chemical Properties]

White to Pale Orange Solid
[Uses]

The Fluorescein Arsenical Hairpin Binder (FlAsH) method is presented for fluorescence labeling of proteins in living cells. Labeling proteins with the membrane-permeant fluorogenic biarsenical dye fluorescein arsenical hairpin binder-ethanedithiol (FlAsH-EDT2). The membrane-permeant fluorogenic biarsenicals FlAsH-EDT2 and ReAsH-EDT2 can be prepared in good yields by a straightforward two-step procedure from the inexpensive precursor dyes fluorescein and resorufin.
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