2797-51-5
2797-51-5 结构式
基本信息
灭藻醌
2-AMINO-3-CHLORO-1,4-NAPHTOQUINONE
ACN
ASISCHEM T86788
MOGETON
QUINOCLAMIN
QUINOCLAMINE
TIMTEC-BB SBB008204
06k
06k-50w
06K-Quinone
1,4-Naphthoquinone, 2-Amino-3-chloro-
2-amino-3-chloro-4-naphthalenedione
2-amino-3-chloro-4-naphthoquinone
2-Amino-3-Chloronaphthoquinone
2-Chloro-3-amino-1,4-naphthoquinone
3-Chloro-2-amino-1,4-naphthoquinone
ACNQ
Mogeton G
Mogeton granule
物理化学性质
environmental
安全数据
Aquatic Acute 1
Aquatic Chronic 1
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Sens. 1A
STOT RE 2
2797-51-5(安全特性,毒性,储运)
常见问题列表
2-氨基-3-氯-1,4-萘醌是重要的有机合成中间体，广泛应用于萘醌类精细化学品的合成。
NF-κB
Quinoclamine causes differentiation of U-937 cells into macrophage-like cells.
Quinoclamine inhibits NF-κB activities in HepG2 cells, with an IC
50
of 1.7 μM.
Quinoclamine (1-4 μM; 30 minutes ) suppresses endogenous NF-κB activity in HepG2 cells through the inhibition of IκB-α phosphorylation and p65 translocation.
Quinoclamine inhibits induced NF-κB activities in lung and breast cancer cell lines.
Quinoclamine affects the expression levels of genes involved in cell cycle or apoptosis.
Quinoclamine down-regulates the expressions of UDP glucuronosyltransferase genes involved in phase II drug metabolism.
Cell Viability Assay
| Cell Line: | HepG2 cells |
| Concentration: | 1 μM, 2 μM, 4 μM, 8 μM, 16 μM, 32 μM, 64 μM |
| Incubation Time: | 24 hours |
| Result: | Inhibited NF-κB activities in HepG2 cells. |
Western Blot Analysis
| Cell Line: | HepG2 cells |
| Concentration: | 0 μM, 1 μM, 2 μM, 4 μM |
| Incubation Time: | 30 minutes |
| Result: | Inhibited IκB-α phosphorylation and p65 translocation in HepG2 cells. |
知名试剂公司产品信息
2-Amino-3-chloro-1,4-naphthoquinone(2797-51-5)