402939-18-8
中文名称
Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem
英文名称
Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem
CAS
402939-18-8
分子式
C19H38N2O
分子量
310.52
MOL 文件
402939-18-8.mol
更新日期
2025/05/22 09:46:39
402939-18-8 结构式
基本信息
中文别名
化合物1-CYCLOHEXYL-3-DODECYL UREA 英文别名
Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem物理化学性质
沸点465.1±12.0 °C(Predicted)
密度0.92±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度Ethanol: 16.67 mg/mL (53.68 mM)
酸度系数(pKa)14.29±0.20(Predicted)
形态Solid
颜色White to off-white
Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | S0548 | Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem 1-Cyclohexyl-3-dodecyl urea | 402939-18-8 | 5mg | 670.48元 |
| 2025/05/22 | S0548 | Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem 1-Cyclohexyl-3-dodecyl urea | 402939-18-8 | 25mg | 3380.33元 |
常见问题列表
生物活性
1-Cyclohexyl-3-dodecyl urea (CDU, N-Cyclohexyl-N-dodecyl urea, NCND) 是一种高选择性的 soluble epoxide hydrolase (sEH) 的抑制剂，可增加 epoxyeicosatrienoic acids (EETs) 的表达水平。靶点
| Target | Value |
|
sEH
() |
体内研究
1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) ( intraperitoneal injection; 3mg/day; 4 days) lowers systolic blood pressure by 30 mm Hg in Ang II hypertensive animals, whereas the corn oil vehicle has no effect on blood pressure in normotensive or Ang II hypertensive animals.
| Animal Model: | Male Sprague-Dawley rats |
| Dosage: | 3mg/day |
| Administration: | Intraperitoneal injection; 4 days |
| Result: | Had antihypertensive properties. |