579-56-6

中文名称盐酸苯氧丙酚胺

英文名称 ISOXSUPRINE HYDROCHLORIDE

CAS 579-56-6

EINECS 编号 209-443-6

分子式 C18H24ClNO3

MDL 编号 MFCD00058069

分子量 337.84

MOL 文件 579-56-6.mol

更新日期 2023/03/20 15:41:19

579-56-6 结构式

基本信息物理化学性质安全数据知名试剂公司产品信息盐酸苯氧丙酚胺价格(试剂级) 常见问题列表

基本信息

中文别名

盐酸苯氧丙酚胺
异舒普林盐酸盐
异克舒令

英文别名

ISOXSUPRINE HCL
ISOXSUPRINE HYDROCHLORIDE
1-(p-hydroxyphenyl)-2-(1’-methyl-2’-phenoxy)ethylaminopropanol-1hydrochlorid
2-(3-phenoxy-2-propylamino)-1-(p-hydroxyphenyl)-1-propanolhydrochloride
isolait
isoxsuprinhydrochloride
p-hydroxy-alpha-(1-((1-methyl-2-phenoxyethyl)amino)ethyl)-benzylalcohohyd
suprilent
vasodilan
vasoplex
Isoxsuprine
Benzenemethanol, 4-hydroxy-.alpha.-1-(1-methyl-2-phenoxyethyl)aminoethyl-, hydrochloride
1-(p-Hydroxyphenyl)-2-(1'-methyl-2'-phenoxy)ethylaminopropanol-1 hydrochloride
Benzenemethanol, 4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (9CI)
Benzyl alcohol, p-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-, hydrochloride (8CI)
Dilavase
Divadilan
Duvadilan
Duviculine
Navilox

所属类别

分析化学：法医和兽医标准品

物理化学性质

熔点203-204°

储存条件Inert atmosphere,2-8°C

溶解度Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in methylene chloride.

酸度系数(pKa)pKa 8.0 (Uncertain);9.8 (Uncertain)

形态neat

颜色White to off-white

CAS 数据库579-56-6(CAS DataBase Reference)

安全数据

危险性符号(GHS) GHS hazard pictograms

GHS07,GHS09

警示词警告

危险性描述H302-H410

防范说明P264-P270-P273-P301+P312-P391-P501

危险品标志Xn

危险类别码R22

安全说明S36

危险品运输编号UN 3077 9 / PGIII

WGK Germany3

RTECS号DO8225000

海关编码2922504500

毒害物质数据579-56-6(Hazardous Substances Data)

毒性LD50 in rats (mg/kg): 1750 orally; 164 i.p. (Goldenthal)

知名试剂公司产品信息

Sigma Aldrich

579-56-6(sigmaaldrich)

盐酸苯氧丙酚胺价格(试剂级)

报价日期	产品编号	产品名称	CAS号	包装	价格
2025/02/08	HY-B1270	盐酸苯氧丙酚胺 Isoxsuprine hydrochloride	579-56-6	200mg	500元
2025/02/08	HY-B1270	盐酸苯氧丙酚胺 Isoxsuprine hydrochloride	579-56-6	10mM * 1mLin DMSO	660元
2025/02/05	S5669	盐酸苯氧丙酚胺 Isoxsuprine hydrochloride	579-56-6	25mg	794.73元

常见问题列表

生物活性

Isoxsuprine hydrochloride是β-肾上腺素能受体（beta-adrenergic）激动剂，具有血管扩张活性。

靶点

Ki: 13.65 μΜ (myometrial beta-adrenergic receptor), 3.48 μΜ (placcntal beta-adrenergic receptor)
NMDA receptor

体外研究

Results show that Isoxsuprine hydrochloride inhibits circular chemorepellent induced defect (CCID) formation dose dependently (5 to 60 μM) and also inhibits 12(S)-HETE synthesis. Furthermore, Isoxsuprine hydrochloride is the only drug inhibiting the induction of all three mobility markers (MLC2, MYPT and paxillin).

体内研究

Total infarct volume in vehicle-treated animals is 279±25 mm ³ compare to 137±18 mm ³ in Isoxsuprine hydrochloride-treated animals.