9024-25-3
中文名称
ACONITASE
英文名称
ACONITASE
CAS
9024-25-3
更新日期
2026/06/26 10:56:27
基本信息
中文别名
乌头酸酶 英文别名
ACO1ACONITASE
EC 4.2.1.3
ACONITATE HYDRATASE
citrate hydro-lyase
Native Porcine Aconitase
ACONITASE, FROM PIG HEART
Ferritin repressor protein
Human ACO1 Protein, His Tag
aconitase from porcine heart
所属类别
生物化工:酶及辅酶类安全数据
安全说明22-24/25
WGK Germany3
存储类别11 - Combustible Solids
毒性Aconitase is the enzyme that reversibly interconverts
citric acid, cis-aconitic acid, and isocitric acid in the
tricarboxylic acid cycle (TCA) (formerly known as the citric
acid or Krebs cycle) by dehydration and hydration reactions.
Aconitase is the target for fluoroacetate, a potent rodenticide,
that condenses with oxaloacetate to yield an aconitase inhibitor
(fluorocitric acid), with resultant accumulation of citric acid
and thus blockage of the TCA cycle, leading to an inhibition
of aerobic energy production.