911637-19-9
中文名称
吉格列汀酒石酸盐
英文名称
GeMigliptin
CAS
911637-19-9
分子式
C18H19F8N5O2
分子量
489.36
MOL 文件
911637-19-9.mol
更新日期
2025/12/08 10:56:00
911637-19-9 结构式
基本信息
中文别名
吉格列汀吉格列汀酒石酸盐
吉格利汀工作对照品
(S)-1-(2-氨基-4-(2,4-双(三氟甲基)-5,8-二氢吡啶并[3,4-D]嘧啶-7(6H)-基)-4-氧代丁基)-5,5-二氟哌啶-2-酮盐酸盐
英文别名
LC15-0444GeMigliptin
GeMigliptin WS
Gemigliptin - G10587
GeMigliptin Tartarate
Gemigliptin Hydrochloride
Product name:-Gemigliptintartarate
(S)-1-(2-Amino-4-(2,4-bis(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one
1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one
2-Piperidinone, 1-[(2S)-2-amino-4-[5,8-dihydro-2,4-bis(trifluoromethyl)pyrido[3,4-d]pyrimidin-7(6H)-yl]-4-oxobutyl]-5,5-difluoro-
所属类别
生物化工：激动剂抑制剂物理化学性质
沸点539.1±50.0 °C(Predicted)
密度1.54±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度DMSO:74.0(Max Conc. mg/mL);151.21(Max Conc. mM)
Ethanol:7.0(Max Conc. mg/mL);14.3(Max Conc. mM)
Water:12.0(Max Conc. mg/mL);24.52(Max Conc. mM)
Ethanol:7.0(Max Conc. mg/mL);14.3(Max Conc. mM)
Water:12.0(Max Conc. mg/mL);24.52(Max Conc. mM)
酸度系数(pKa)7.33±0.10(Predicted)
形态Solid
颜色White to orange
InChIInChI=1S/C18H19F8N5O2/c19-16(20)3-1-12(32)31(8-16)6-9(27)5-13(33)30-4-2-10-11(7-30)28-15(18(24,25)26)29-14(10)17(21,22)23/h9H,1-8,27H2/t9-/m0/s1
InChIKeyZWPRRQZNBDYKLH-VIFPVBQESA-N
SMILESN1(C[C@@H](N)CC(N2CC3C(CC2)=C(C(F)(F)F)N=C(C(F)(F)F)N=3)=O)CC(F)(F)CCC1=O